Report Scope:

This report is an overview of the pharmaceutical industry landscape and active pharmaceutical ingredients (API), along with the current trends and dynamics shaping the API market landscape. API sourcing trends and regulatory guidelines that impact the procurement of APIs are studied here. The increasing importance of outsourced API manufacturing activities and the impact on the pharmaceutical industry are covered in the report.

In this report, the API market is segmented into molecular entity, manufacturer type, end use, and region. Further, it is segmented into two molecular entity groups: natural and synthetic API. Synthetic APIs are further segmented into chemical synthesis, biocatalytic and cell culture. Under the category of molecular entity, APIs are segmented into small molecules and large molecules. By sourcing type, the market is segmented into the captive market, merchant market and contract manufacturing organization (CMO). In terms of end use, the market is segmented into clinical trial use and commercial use.

In terms of geography, this report analyzes the market by the following regions: North America, Europe, Asia-Pacific, and Rest of the World (Latin America and the Middle East). The API market is very fragmented. Therefore, attempts have been made to present the market share held by selected companies.

Report Includes:

- 27 data tables and 32 additional tables
- An overview of the global active pharmaceutical ingredients (API) market
- Estimation of the market size and analyses of market trends, with data from 2018, 2019, estimates for 2020 and projection of CAGR through 2025
- Highlights of quantitative and qualitative data of the API market by molecular entity, manufacturer type, origin, end use and region
- Detailed description of API sources, production methods, route of synthesis, and contract manufacturing organizations
- Information on regulatory perspective on production methods of API and discussion on harmonization of API GMP standards and supply chain integrity
- Impact analysis of coronavirus on the global economy; and discussion on impact of COVID-19 on API industry
- Identification of market drivers, restraints and other forces impacting the global market and evaluation of current market trends, market size, market forecast, and technological advancements within the industry
- Discussion on issues like patent expiry and its impact on the pharmaceutical market, and details of changes in pharmaceutical drug development
- Coverage of events like mergers & acquisitions, joint ventures, collaborations or partnerships, and other key market strategies
- Company profiles of major players of the industry, including Actavis PLC, BASF AG, Cambrex Corp., GlaxoSmithKline PLC and Sun Pharmaceutical Industries Ltd.

ical Ingredients - Introduction
Pharmaceutical Industry Overview
Patent Expiry Impact on the Pharmaceutical Market
Changes in Pharmaceutical Drug Development
Drug Discovery and Development Process
Target Identification and Validation
Technologies for Drug Discovery
Pharmaceutical Business Model
Pharmaceutical Market Dynamics
The Cost of Drug Development
Global Pharmaceutical Supply Chain
API Defined
Sources of APIs
API Production Methods
API Production: Route of Synthesis
Production Methods
Active Pharmaceutical Ingredient Market
Market Dynamics
Market Drivers
Market Challenges
Emerging Trends
Impact of COVID on API Production and Supply Chain
API Pricing Trends and Increases Amidst COVID-19
Porter's Five-Force Analysis in the API Market
Threat of New Entrants
Threat of Substitute Products or Services
Bargaining Power of Customers (Buyers)
Bargaining Power of Suppliers
Intensity of Competitive Rivalry
Current State of Active Pharmaceutical Ingredient Regulations
Harmonization of API GMP Standards and Supply Chain Integrity
CMO/CDMO Regulations
Regulation in the U.S.
Regulation in Europe
Chapter 4 Active Pharmaceutical Ingredients Market by Manufacturer/ Service Provider
Introduction and Global Markets
The API Market by Manufacturer Type
Captive Market: Market Analysis
Overview
Market Size and Forecast
Merchant Market: Market Analysis
Overview
Market Size and Forecast
Contract Manufacturing Organizations (CMOs): Market Analysis
Overview
Market Size and Forecast
Chapter 5 Active Pharmaceutical Ingredients Market by End Use
Introduction and Global Markets
Clinical Trial: Market Analysis
Overview
Market Size and Forecast
Commercial: Market Analysis
Overview
Market Size and Forecast
Chapter 6 Active Pharmaceutical Ingredients by Origin
Introduction and Market Analysis
Natural Origin: Types and Market Analysis
Plant Sources
Animal Sources
Others
Market Size and Forecast
Synthetic APIs: Types and Market Analysis
Overview
Market Size and Forecast
Chemical Synthesis: Introduction and Market Analysis
Biocatalysis: Introduction and Market Analysis
Cell Culture Methods: Introduction and Market Analysis
Chapter 7 Active Pharmaceutical Ingredients Market by Molecule Type
Introduction and Global Markets
Small Molecules: Types and Market Analysis
Market Size and Forecast
Branded Small Molecule APIs
Generic APIs
Biologics: Types and Market Analysis
Top-Selling Biologics
Market Size and Forecast
Branded Biologic APIs
Biosimilar APIs
Chapter 8 Active Pharmaceutical Ingredients Market by Region
Introduction
North America
Overview
Market Size by Country
Europe
Overview
Market Size by Country
Asia-Pacific
Overview
API Production in Asia-Pacific
Market Size by Country
Rest of the World
Overview
Chapter 9 Supplier Landscape and Key Industry Developments
Supplier Landscape
Captive Manufacturers
Merchant API Manufacturers
CMOs/CDMOs
API Fragmentation: -Reasons for Fragmented Industry Structure
Recent Industry and Investment Activities
Impact of COVID-19 on API Manufacturers
Chapter 10 Company Profiles
ABBVIE CONTRACT MANUFACTURING
AESICA PHARMACEUTICALS LTD.
AUROBINDO PHARMA
ACTAVIS PLC
ALBANY MOLECULAR RESEARCH INC. (AMRI)
AVID BIOSERVICES INC.
BASF AG
BOEHRINGER INGELHEIM
CAMBREX CORP.
CIPLA
CSPC PHARMACEUTICAL GROUP
CORDEN PHARMA INTERNATIONAL GMBH
DISHMAN GROUP
DIVIS LABORATORIES LTD.
DR REDDY’S LABORATORY
FAREVA GROUP
GLAXOSMITHKLINE PLC
HALO PHARMA
HETERO
JOHNSON MATTHEY PHARMACEUTICAL MATERIALS INC.
JUBILANT LIFE SCIENCES LTD.
LONZA
LUPIN
MERCK KGAA
MYLAN N.V.
NOVARTIS AG
PATHEON
PFIZER CENTREONE
PIRAMAL PHARMA SOLUTIONS
SHANDONG XINHUA PHARMACEUTICAL CO. LTD.
SIEGFRIED AG
SUN PHARMACEUTICAL INDUSTRIES LTD.
TEVA PHARMACEUTICAL INDUSTRIES, INC.
WUXI APPTEC
ZHEJIANG CHEMICALS IMPORT/EXPORT CORP.
ZHUHAI UNITED LABORATORIES CO. LTD.
Chapter 11 Appendix: Abbreviations
Abbreviations